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The Neurospora tetrasperma mating-type chromosomes have been shown to be structurally heterozygous by reciprocal introgression of these chromosomes between N. tetrasperma and N. crassa. This structural heterozygosity correlates with both a previously described recombination block and cytologically visible unpaired chromosomes at pachytene. Genes on the autosomes are also implicated in blocking recombination.

Blocked Recombination Along the Mating-Type Chromosomes of Neurospora tetrasperma Involves Both Structural Heterozygosity and Autosomal Genes