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In adult animals the intramuscular injection of hCG was followed by a rapid rise in plasma testosterone levels within 2-3 h and at doses of 40 and 80 i.u. hCG this primary response was followed by a second peak of testosterone at 48 h. Prepubertal marmosets also responded to hCG stimulation with a rapid increase in plasma testosterone levels within 3 h, but the magnitude of this peak was lower than that observed in adult animals and no biphasic pattern was observed. In adult and prepubertal animals a second dose of hCG (40 i.u.) administered 24 h after the initial injection failed to produce a further rapid increment in plasma testosterone levels.

Plasma testosterone response to hCG stimulation in the male marmoset monkey (Callithrix jacchus jacchus)