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Romney ewes were artificially inseminated at the oestrus after treatment with PMSG on Day 12 of the cycle, Cloprostenol on Day 14, or both. PMSG resulted in increased numbers of ovulations and large follicles but Cloprostenol had no effect alone or with PMSG, PMSG and Cloprostenol alone led to reduced proportions of eggs fertilized, and PMSG also reduced the proportion of ewes with fertilized eggs. The distribution of eggs in the reproductive tract indicated more rapid egg transport in ewes treated with PMSG. A greater proportion of eggs was recovered from the uterus in ewes in which oestrus was first detected at night. Cloprostenol, as administered to PMSG-treated ewes in this trial, offered no advantage for the preparation of donor ewes for egg transfer.

Effects of PMSG and the prostaglandin F-2 analogue, cloprostenol, on superovulation, fertilization and egg transport in the ewe