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Luteal-phase progesterone levels in 5 beagle bitches fell to 0.3-0.4 ng/ml within 3-17 days after hypophysectomies on Day 10-50 of the cycle. Plasma progesterone in 6 bitches increased (P &lt; 0.01) within 3 h after LH (100 microgram/kg) injection between Days 35 and 55 of the cycle. Normal luteal function in the bitch appears to require continuous pituitary trophic support perhaps involving LH.

Effects of hypophysectomy and of LH administration on luteal phase plasma progesterone levels in the beagle bitch