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Outbred female mice were exposed during 3 oestrous cycles and mated to outbred or C57BL/kw males. Although ovulation number (CL and flushed eggs) was similar in all females, there were significantly fewer (P &lt; 0.01) fertilized eggs and implantations in females exposed and mated to C57BL/kw males. Exposure to outbred males and mating with C57BL/kw males led to some improvement but the best results were obtained with females mated to outbred males. The activity of uterine dehydrogenases on Day 4 of pregnancy was also greatest in females mated to outbred males. It is concluded that the pheromonal stimulation leads to hormone concentration differences which affect implantation.

Male-pheromone effect on the efficiency of pregnancy in female mice