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The spontaneous meiotic maturation of cumulus-free oocytes was not affected by progesterone or oestradiol-17beta at 2 microgram/ml, but both steroids decreased polar body production at 10 microgram/ml and progesterone decreased the number undergoing germinal vesicle breakdown.

Effects of progesterone and oestradiol-17 on the spontaneous meiotic maturation of mouse oocytes