English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Ovulation can be induced in mice and rats by various types and combinations ofgonadotrophins, as well as by synthetic LH-RH following pretreatment with PMSG (see Stern & Schuetz, 1970; Gosden & Readhead, 1974). The present work was undertaken to establish whether LH-RH and an analogue could induce ovulation in dioestrous mice without pretreatment with PMSG. Adult (30 \m=+-\5 g) virgin Swiss albino mice were maintained in an air-conditioned room (24-25\s=deg\C; 45-50% humidity) and exposed to equal periods of light and darkness. The decapeptides used were: (1) synthetic LH-RH (AY-24,031): H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, and (2) LH-RH analogue (AY-25,205): H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NH-CH2-CH3. The freeze-dried decapeptides were injected i.p. in 0\m=.\2ml of 0\m=.\1%gelatin/0\m=.\9%saline between 15.00 and 15.30 hours on the day of dioestrus which was determined from examination of vaginal smears and recognition of the day of pro-oestrus. No distinction was made between animals with 4-day and 5-day cycles. Control mice received injections of the vehicle only. Evidence for ovulation was obtained by counting the eggs in the oviducts on the morning after the injection. The results were assessed by the fourfold contingency test tables of Mainland & Murray (1952).

Induction of ovulation in adult mice with a synthetic LH-RH (AY-24,031) and an analogue (AY-25,205)