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A technique for perfusion of the rabbit ovary in vivo is described which allows a quantitative determination of the intra-ovarian passage from artery to vein of 15 \m=+-\5 \g=m\mnon-radioactive microspheres. The passage of microspheres was less than 1 % in ovaries containing follicles (from non-pregnant rabbits) as well as in ovaries containing CL (from rabbits in different stages ofpseudopregnancy). Addition ofa vasodilator to the perfusion system did not influence the result. The present results do not indicate that arterio-venous shunts of physiological significance exist in the rabbit ovary.

SEARCH FOR ARTERIO-VENOUS SHUNTS IN THE RABBIT OVARY IN SITU USING PERFUSION OF MICROSPHERES