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Treatment of adult male rats with oestradiol, cyproterone acetate or cyproterone affected spermatogenesis, accessory sexual glands and fertility in different ways. Suppression ofLeydig cells, spermatogenesis, accessory sexual glands and fertility ran parallel in oestradiol-treated animals. High doses of cyproterone acetate caused severe suppression of the accessory sexual glands and fertility but had only a slight inhibitory influ-

reproduction

COMPARISON OF THE EFFECTS OF CYPROTERONE, CYPROTERONE ACETATE AND OESTRADIOL ON TESTICULAR FUNCTION, ACCESSORY SEXUAL GLANDS AND FERTILITY IN A LONG-TERM STUDY ON RATS