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1Departments of Human Genetics, Medicine and Oncology, McGill University, Montreal, Québec, Canada 2Department of Endocrinology, Cochin Hospital, Paris Descartes University, Paris, France 3Genomic Medicine Institute, Lerner Research Institute and Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA 4Department of Genetics and Genome Sciences and Germline High Risk Focus Group, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

65 YEARS OF THE DOUBLE HELIX: It’s all in the DNA: understanding and managing endocrine neoplasms