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• Anti-Mullerian hormone (AMH) is a member of transforming growth factor β (TGF-β) • Produced by human granulosa cells • AMH inhibits initiation of primordial follicle growth • AMH inhibits FSH-stimulated follicle growth • Negative correlation between AMH retrieved in fluid from small antral follicles and Cyp19A1 mRNA •AMH reduces the expression of aromatase CYP19A1 induced by FSH • Gonadotropins treatment (using LH or FSH) induce strong expression of both aromatases Cyp19A1 and P450scc Material and Methods

rhAMH inhibits CYP19 and P450scc mRNA expression in granulosa-lutein cells treated with gonadotropin