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Chronic heart failure (HF) is a major cause of morbidity and mortality in humans and domestic animals. HF is a systemic condition characterised by chronic inflammation and functional changes in non-cardiovascular tissues; obesity is also associated with low level chronic inflammation, with adipose tissue (AT) exhibiting infiltration of macrophages and alterations in fatty acid (FA) profiles(1).

Impact of chronic heart failure on adipose tissue functional plasticity: a role for fatty acids?