Open AccessIn vitro study of the effect of raloxifene on lipid metabolism compared with tamoxifen
Author(s) -
Yasuo Hozumi,
Miyuki KawanoKawada,
V. Craig Jordan
Publication year - 2000
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1430427
Subject(s) - raloxifene , triglyceride , endocrinology , medicine , tamoxifen , chemistry , oleic acid , selective estrogen receptor modulator , antiestrogen , low density lipoprotein , cholesterol , estrogen , lipoprotein , biochemistry , breast cancer , cancer
Tamoxifen and raloxifene, selective estrogen receptor modulators, decrease serum concentrations of total cholesterol; however, the effect of these drugs on triglyceride metabolism is unclear. In the present study, we investigated the in vitro effect of raloxifene on lipid metabolism and compared it with that of tamoxifen.
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