Open AccessIncreased sensitivity to the inhibitory effect of excess iodide on thyroid function in patients with beta-thalassemia major and iron overload and the subsequent development of hypothyroidism
Author(s) -
Theodore K. Alexandrides,
Neoklis A. Georgopoulos,
S. Yarmenitis,
A. G. Vagenakis
Publication year - 2000
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1430319
Subject(s) - medicine , endocrinology , subclinical infection , thyroid , thyroid function , thyroid peroxidase , thyroid function tests , iodide , iodine , hormone , thyroid disease , endocrine system , chemistry , organic chemistry
Patients with beta-thalassemia frequently develop primary hypothyroidism and other endocrine disorders due to iron overload. We studied whether administration of excess iodide to patients with apparently normal thyroid function could uncover an underlying thyroid disease.
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