Open AccessLH and FSH secretory responses to GnRH in normal individuals: a non-parametric deconvolution approach
Author(s) -
Giuseppe De Nicolao,
Diego Liberati,
J. D. Veldhuis,
Alessandro Sartório
Publication year - 1999
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1410246
Subject(s) - endocrinology , medicine , bolus (digestion) , hormone , deconvolution , stimulus (psychology) , endogeny , secretion , luteinizing hormone , chemistry , psychology , mathematics , algorithm , psychotherapist
To reconstruct the instantaneous secretion rate (ISR) of LH and FSH after GnRH administration in normal volunteers using non-parametric deconvolution, and to derive a direct integration formula to evaluate the amount of LH and FSH secreted during the first 60 min after the stimulus.
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