Open AccessGenetic influence on the associations between IGF-I and glucose metabolism in a cohort of elderly twins
Author(s) -
Rikke Beck Jensen,
Ajay Thankamony,
Klaus K. Holst,
J. A. M. J. L. Janssen,
Anders Juul,
David B. Dunger,
Pernille Poulsen,
Thomas Scheike
Publication year - 2017
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-17-0754
Subject(s) - medicine , endocrinology , cohort , confounding , heritability , monozygotic twin , anthropometry , twin study , insulin , carbohydrate metabolism , biology , genetics
IGF-I may be a marker of later metabolic and cardiovascular disease. The interactions between IGF-I and glucose metabolism are multifactorial, and there is potential confounding from several secondary effects. In this study, we examined the interaction between IGF-I and glucose metabolism in a large cohort of clinically well-characterized elderly twins.
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