Open AccessHistory before diagnosis in childhood craniopharyngioma: associations with initial presentation and long-term prognosis
Author(s) -
Anika Hoffmann,
Svenja Boekhoff,
U Gebhardt,
Anthe S. Sterkenburg,
Anna M. Daubenbüchel,
Maria Eveslage,
Hermann L. Müller
Publication year - 2015
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-15-0709
Subject(s) - craniopharyngioma , presentation (obstetrics) , term (time) , medicine , pediatrics , endocrinology , surgery , physics , quantum mechanics
Childhood craniopharyngiomas (CP) are often diagnosed after a long duration of history (DOH). Tumor size, hypothalamic involvement (HI), and obesity are associated with reduced overall survival (OS) and functional capacity (FC). The effect of DOH and specific symptoms in history on presentation at initial diagnosis and long-term prognosis are unknown.
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