Open AccessGenetic analysis in young patients with sporadic pituitary macroadenomas: besides AIP don't forget MEN1 genetic analysis
Author(s) -
Thomas Cuny,
Morgane Pertuit,
Mona Sahnoun-Fathallah,
Adrian Daly,
Gianluca Occhi,
MarieFrançoise Odou,
Antoine Tabarin,
M.L. Nunès,
Brigitte Delemer,
V. Rohmer,
Rachel Desailloud,
V. Kerlan,
Olivier Chabre,
JeanLouis Sadoul,
Muriel Cogne,
Philippe Caron,
Christine CortetRudelli,
Anne Lienhardt,
I. Raingeard,
A.M. Guedj,
Thierry Brue,
Albert Beckers,
G. Weryha,
A Enjalbert,
Anne Barlier
Publication year - 2013
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-12-0763
Subject(s) - men1 , multiple endocrine neoplasia , prolactinoma , germline mutation , context (archaeology) , medicine , population , mutation , endocrinology , genetics , gastroenterology , biology , gene , prolactin , paleontology , environmental health , hormone
Germline mutations in the aryl hydrocarbon receptor interacting protein gene (AIP) have been identified in young patients (age ≤30 years old) with sporadic pituitary macroadenomas. Otherwise, there are few data concerning the prevalence of multiple endocrine neoplasia type 1 (MEN1) mutations in such a population.
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