Open AccessAutomated image analysis of hand radiographs reveals widened joint spaces in patients with long-term control of acromegaly: relation to disease activity and symptoms
Author(s) -
Nienke R. Biermasz,
Ronald van ’t Klooster,
M. J. E. Wassenaar,
Steve H. Malm,
Kim M. J. A. Claessen,
Rob G. H. H. Nelissen,
Ferdinand Roelfsema,
Alberto M. Pereira,
Herman M. Kroon,
Berend C. Stoel,
Johannes A. Romijn,
M. Kloppenburg
Publication year - 2011
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-11-0795
Subject(s) - acromegaly , medicine , arthropathy , interphalangeal joint , osteoarthritis , metatarsophalangeal joints , radiography , confidence interval , rheumatology , joint pain , complication , womac , surgery , pathology , growth hormone , alternative medicine , hormone
Arthropathy is an invalidating complication of acromegaly. Although acromegalic arthropathy shares features with primary osteoarthritis, joint spaces are widened rather than narrowed in patients with long-term cure of acromegaly. The late effects of acromegaly on hand joints have not been characterized. Therefore, the objective of the current study was to assess joint space widths (JSWs) of hand joints in patients with long-term control of acromegaly and to identify factors associated with JSW.
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