Open AccessAnti-mullerian hormone is associated with advanced glycosylated end products in lean women with polycystic ovary syndrome
Author(s) -
Evanthia DiamantiKandarakis,
Athanasia Piouka,
Sarantis Livadas,
Christina Piperi,
Ilias Katsikis,
Athanasios G. Papavassiliou,
D. Panidis
Publication year - 2009
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-08-0510
Subject(s) - polycystic ovary , anovulation , endocrinology , medicine , anti müllerian hormone , follicle , hormone , oocyte , ovary , ovulation , diabetes mellitus , biology , insulin resistance , embryo , microbiology and biotechnology
Oocyte maturation process characterizes polycystic ovary syndrome (PCOS). The mechanisms of this abnormality leading to chronic anovulation are under investigation. Advanced glycosylated end products (AGEs), a marker of oxidative stress linked with oocyte maturation are localized in granulosa cells and are increased in sera, in women with PCOS. The aim of this study was to investigate the relationship, whether there is an association between the anti-mullerian hormone (AMH), a hormone produced by granulosa cells and AGEs in ovulatory and anovulatory PCOS (PCOS-Anov), as well as in non-PCOS anovulatory (Non-PCOS Anov) women. Design Cross-sectional study.
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