Open AccessDecreased lipin 1β expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome
Author(s) -
Barbara Mlinar,
Marija Pfeifer,
Eda Vrtačnik Bokal,
Mojca Jensterle,
Janja Marc
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-08-0387
Subject(s) - medicine , endocrinology , polycystic ovary , insulin resistance , adipose tissue , waist , adiponectin , body mass index , insulin
In polycystic ovary syndrome (PCOS), insulin resistance (IR) appears with high prevalence and represents the major cause of cardiometabolic complications. Lipin 1beta regulates lipid metabolism and augments insulin sensitivity. The impact of lipin 1beta expression in visceral and subcutaneous adipose tissue of PCOS patients on IR was studied for the first time.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom