Open AccessNormalization of catecholamine production following resection of phaeochromocytoma positively influences carotid vascular remodelling
Author(s) -
Giampaolo Bernini,
Fabio Galetta,
Ferdinando Franzoni,
Michele Bardini,
Chiara Taurino,
Angelica Moretti,
M. Bernini,
Piero Berti,
Paolo Miccoli,
Antonio Salvetti
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-08-0126
Subject(s) - medicine , blood pressure , pheochromocytoma , intima media thickness , cardiology , catecholamine , endocrinology , normetanephrine , urology , gastroenterology , carotid arteries
To evaluate the influence of plasma catecholamines on the vascular structure in humans, the effects of catecholamine normalization on the carotid wall of patients with phaeochromocytoma (PHEO) were investigated. A prospective study in patients with PHEO before and after (first follow-up: 20.5+/-1.8 months, second follow-up: 31.5+/-2.2 months) successful surgery was conducted in the University Referral Center for Blood Pressure Diseases. Ten consecutive patients with PHEOs and ten age- and blood pressure-matched controls were investigated. Intima-media thickness (IMT) by two-dimensional conventional ultrasonography and corrected ultrasonic integrated backscatter signal (C-IBS) analysis of carotid arteries were investigated in basal conditions and after mass removal.
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