Open AccessIncretin levels in polycystic ovary syndrome
Author(s) -
Jana Vrbíková,
Martin Hill,
Běla Bendlová,
Tereza Grimmichová,
Kateřina Komrsková,
K Vondra,
Giovanni Pacini
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-08-0097
Subject(s) - polycystic ovary , medicine , endocrinology , incretin , ovary , insulin , diabetes mellitus , insulin resistance , type 2 diabetes
Polycystic ovary syndrome (PCOS) has been linked to a high risk of type 2 diabetes mellitus. Disturbances in the secretion of the incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) have been observed in states with impaired glucose regulation. This paper considers the secretion of GIP and GLP-1 after oral glucose load in a group of lean, glucose-tolerant PCOS women in comparison with age- and body mass index (BMI)-matched healthy women.
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