Open AccessCirculating high-molecular-weight adiponectin is upregulated in preeclampsia and is related to insulin sensitivity and renal function
Author(s) -
Mathias Faßhauer,
Theresa Waldeyer,
Jeannette Seeger,
Susanne Schrey-Petersen,
Thomas Ebert,
Jürgen Kratzsch,
Ulrike Lössner,
Matthias Blüher,
Michael Stümvoll,
R Faber,
Holger Stepan
Publication year - 2008
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-07-0454
Subject(s) - adiponectin , adipokine , medicine , endocrinology , preeclampsia , insulin , insulin resistance , downregulation and upregulation , renal function , pregnancy , chemistry , biology , genetics , biochemistry , gene
Preeclampsia (PE) is a serious cardiovascular complication in pregnancy which is associated with an increased future metabolic and cardiovascular risk for mother and newborn. Recently, a paradoxical upregulation of the insulin-sensitizing and anti-atherogenic adipokine adiponectin has been shown in PE. Furthermore, high-molecular-weight (HMW) adiponectin has been suggested as the biologically active form of this adipokine.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom