Retinol-binding protein 4 levels are elevated in polycystic ovary syndrome women with obesity and impaired glucose metabolism
Author(s) -
Susanne Hahn,
Manuel Backhaus,
Martina BroeckerPreuss,
Susanne Tan,
Tiina Dietz,
Rainer Kimmig,
Markus Schmidt,
Klaus Mann,
Onno E. Janßen
Publication year - 2007
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-07-0143
Subject(s) - medicine , endocrinology , retinol binding protein 4 , insulin resistance , polycystic ovary , adipokine , body mass index , type 2 diabetes , obesity , carbohydrate metabolism , diabetes mellitus
Insulin resistance and obesity are common features of the polycystic ovary syndrome (PCOS). Retinol-binding protein 4 (RBP4), a new fat-derived adipokine, has been described to be elevated in obesity and type 2 diabetes. The aim of the present study was to investigate whether serum RBP4 levels are correlated with metabolic parameters, indices of insulin resistance, and endocrine variables in German PCOS women.
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