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All subjects were identified utilizing national health registries which cover the whole Danish population. In women aged ≥55 with an OP diagnosis, we assessed the effect of postdiagnosis GI events on treatment initiation (n=34,614). In women aged ≥55 who initiated an oral bisphosphonate, we determined the likelihood of discontinuation after 12 months in patients with and without GI events (n=60,291). In a matched subset of post-OP treated patients with (n=1,373) and without (n=43,680) GI events (cases and controls, respectively), health care resource use and cost were tallied during the year after the first GI event. Subjects in the three analyses were identified within years 2002-2009.

bone abstracts

Effect of gastrointestinal events on treatment patterns, discontinuation, resource utilization, and cost in osteoporosis: an analysis using danish health registries