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The results confirmed that there was an inverse relationship between levels of osteocalcin and body fat content. The concomitant reduction in bone resorption of OB rats, may suggest a decrease in the biological active osteocalcin that could be the responsible of the observed increment in fasting glucose levels and insulin resistance. The study was partially supported by UBACyT 20020100100320 and CONICET Karsenty G et al., 2012

Interrelationship between osteocalcin (bgp) and energetic metabolism in two strains of rats