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Although monoclonal antibodies against human FSH are widely available, monoclonal antibodies generated against FSH from non-human species are less common, and presently none against ovine FSH are available. Monoclonal antibodies against different epitopes on FSH are useful in studies of the relationship between FSH structure and activity, for purifying FSH by immunoaffinity chromatography, and for developing homologous, nonradioactive, noncompetitive irnmunoassays for FSH. The purpose of this study was to produce monoclonal antibodies to ovine(o) FSH.

Generation of monoclonal antibody to ovine FSH and its application in immunoneutralization and enzymeiminunoassay