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Substance use is associated with poor mental health, but little is known regarding how use of multiple substances is associated with mental health, particularly longitudinally, in community studies. This article examines this issue in a large (N = 710), natural-history study of rural stimulant (cocaine and/or methamphetamine) users in three states.

journal of studies on alcohol and drugs

Longitudinal Relationship Between Psychological Distress and Multiple Substance Use: Results From a Three-Year Multisite Natural-History Study of Rural Stimulant Users