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Ovarian stromal hyperthecosis in post-menopausal women is a rare disorder characterised by gradual virilisation and features of the metabolic syndrome similar to PCOS.1 Improvement of diabetic control in hyperthecosis has been reported following oophorectomy, perhaps secondary to normalisation of the hyperandrogenaemia.2 This is a report of worsening diabetes following oophorectomy. The case and possible explanations for the response are described.

Paradoxical glycaemic response to surgical treatment of ovarian hyperthecosis in a patient with type 2 diabetes