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We report a case of exaggerated weight reduction with com bination therapy of liraglutide and dapagliflozin. The patient achieved a loss in excess body weight (EBW) of 73.5 kg or 40.3% and a reduction in HbA 1c from 83 mmol/mol (9.7%) to 36 mmol/mol (5.4%) in response to the combination therapy of oral dapagliflozin with subcutaneous liraglutide and concurrent discontinuation of subcutaneous insulin.

Combining SGLT2 inhibitor and GLP-1 agonist: exaggerated weight loss in a morbidly obese patient with type 2 diabetes