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Dengue fever is the one of danger disease caused by dengue virus which is infected through species of mosquito Aedes aegypti. Chemical insecticides has been concidered to the development of the resistance in the mosquito species as the impact in vector control. This research aims to analyze the potential of papaya (Carica papaya) leaf as larvacides. Phytochemical screening of metanolic extract Carica papaya leaf indicated, it has secondary metabolites contain such as plavonoids, terpenoids, saponins, and alkaloids which have been known as toxic to the most of insect include larva of Aedes aegypti. The effect of larvae have been investigated in 4th and 5th for 48 hours with five different concentrations 0,25% 0,5% 0,75% and 1%, abate as positive control and aquades negative control. Lethal concentration of larvae have been investigated and determined by probit analyze. The bioassay showed that LC50 methanolic extract of Papaya leaf (Carica papaya) has an effect to Aedes aegypti LC50 2,5%.. Keywords— Dengue, Papaya, Aedes, Biolarvacide.

Larvacidal Efficacy of Methanolic Extract Papaya (Carica papaya) Leaves against the Vector Mosquito Aedes aegypti