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44 Ti/ 44 Sc radionuclide generators are of interest for molecular imaging. The 3.97 h half-life of   44 Sc and its high positron branching of 94% may stimulate the application of   44 Sc labelled PET radiopharmaceuticals. However, both   44 Ti production and   44 Ti/ 44 Sc generator design represent challenges for basic radiochemistry.

A 44 Ti/ 44 Sc radionuclide generator for potential application of 44 Sc-based PET-radiopharmaceuticals