English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Ceragenins (CSAs) are a new class of antimicrobial agents that display broad spectrum antibacterial activity and may find use in the treatment of various infections. A member of this class CSA-13 was labelled with  99m Tc using SnCl 2 ·H 2 O as a reducing agent. The labelling efficiency depended on the ligand/reductant ratio, pH and volume of the reaction mixture. The radiochemical purity and stability of  99m Tc-CSA was determined by thin layer chromatography. Biodistribution studies of  99m Tc-CSA were performed in Sprague Dawley rats. Liver and spleen uptake was quite high. A significantly higher accumulation of  99m Tc-CSA was seen at sites of   S. aureus   infected rats. The results were compared with  99m Tc-Ciprofloxacin.

Preparation, quality control and biological evaluation of 99m Tc-labelled cationic steroid antibiotic (CSA-13)