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Copper-64 ( t  ½  = 12.7 h) is a promising cancer treatment radiotherapy agent and combines positron emission tomography (PET). It was produced utilizing the  64 Ni(p,n)  64 Cu nuclear reaction channel. Natural nickel was electroplated successfully, 48 μm thick, onto a gold-coated copper backing slab. Bombardment of nickel plated target was performed with 16 MeV protons at a current of 200 μA. Copper-64 together with copper-61 was separated from Ni and other non-isotopic impurities by ion exchange chromatography. The method of separation of radiocopper has been improved.

Radiochemical studies relevant to the no-carrier-added production of 61,64 Cu at a cyclotron