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C17H17NO3, orthorhombic, Pbca (no. 61), a = 14.888(3) Å, b = 10.331(2) Å, c = 17.724(4) Å, V = 2726.3 Å, Z = 8, Rgt(F) = 0.057, wRref(F) = 0.142, T = 93 K. Source of material Sinomenine is produced from the powder of the roots of Sinomenium acutum by the Baoji Yongjia Plant Medicine Extracting Limited Company, Baoji, P. R. China. It is obtained from the benzene extract of the powder in vacuum [1]. The remaining mother benzene liquor (3 kg), after the extraction of sinomenine, was obtained from the company. It was subjected to repeated chromatography on a silica gel column to afford the title compound (10 mg) and several other alkaloids together. Orange single crystals of the title compound suitable for single crystal X-ray analysis were obtained after repeated recrystallization from acetone at room temperature. Discussion Sinomenium acutum is distributed mainly in hilly regions of southwest, northwest and southeast China. The roots and stems of the plant are used as herb medicine to cure rheumatism, dropsy and dermatophytosis. A number of alkaloids with different kinds of skeletons have been isolated from the plant [2-5]. In the course of our systematic search for bioactive substances from Chinese traditional herb medicine, we have studied the remaining mother benzene liquor of roots of Sinomenium acutum and obtained several alkaloids, including the title compound. Its optical isomer representing a new skeleton alkaloid with the cell-protective effects has been recently isolated from the roots of Sinomenium acutum [6]. In the process of related studies, we have already reported the isolation and crystal structures of cheilanthifoline [7], 8-oxotetrahydropalmatine [8], tetrahydroepiberberine [9], 8oxocanadine [10], sinoacutine [11] and 8-demethoxyrunanine [12]. The title compound is composed of four rings A, B, C and D. Ring A is a benzene ring, with an attached hydroxyl at C4 and methoxyl at C3 which are essentially coplanar to A. Ring B adopts half-chair conformation. Both rings C and D adopt halfchair conformation and are nearly perpendicular to each other. Ring D is an N-methyl tetrahydrofuran. Compared to its optical isomer [6], the crystal structure of (+)-sinoracutine presents different crystal system, space group, unit cell dimensions and density. Z. Kristallogr. NCS 225 (2010) 733-734 / DOI 10.1524/ncrs.2010.0323 733 © by Oldenbourg Wissenschaftsverlag, München Crystal: orange block, size 0.20 × 0.43 × 0.50 mm Wavelength: Mo K+ radiation (0.71073 Å) .: 0.95 cm−1 Diffractometer, scan mode: AFC10/Saturn724+, #/% 2,max: 54.96° N(hkl)measured, N(hkl)unique: 20518, 3122 Criterion for Iobs, N(hkl)gt: Iobs > 2 )(Iobs), 2953 N(param)refined: 204 Programs: SHELXS-97, SHELXL-97 [13] Table 1. Data collection and handling. H(1) 8c 0.4810 0.3783 0.3829 0.029 H(2) 8c 0.6054 0.5147 0.3695 0.026 H(7) 8c 0.3717 0.0871 0.5531 0.035 H(8) 8c 0.3900 0.2295 0.4565 0.032 H(11A) 8c 0.5587 0.3960 0.6617 0.026 H(11B) 8c 0.4965 0.2873 0.7004 0.026 H(12A) 8c 0.6539 0.3549 0.7585 0.030 H(12B) 8c 0.6102 0.2148 0.7744 0.030 H(14) 8c 0.6912 0.0971 0.5952 0.025 H(16) 8c 0.4720 −0.0604 0.6531 0.036 H(17A) 8c 0.8063 0.6741 0.4106 0.028 H(17B) 8c 0.6995 0.6851 0.4020 0.028 H(17C) 8c 0.7530 0.5733 0.3586 0.028 Table 2. Atomic coordinates and displacement parameters (in Å). Atom Site x y z Uiso

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Crystal structure of 11-hydroxy-10-methoxy-3-methyl-1,2,3,3a-tetrahydro-4H-benzo[6,7]indeno[1,7a-b]pyrrol-4-one, C 17 H 17 NO 3 , a (+)-sinoracutine at 93 K