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Inclusions containing α-synuclein are considered the major pathologic hallmark of a subgroup of neurodegenerative diseases, including Parkinson's disease (PD) and Lewy body dementia. In these so-called synucleinopathies, α-synuclein (normally a tetrameric soluble protein) appears as oligomers and

Yet Another Role for SIRT1: Reduction of α-Synuclein Aggregation in Stressed Neurons