English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background: Infection with human papillomavirus (HPV) has been identified as the primary cause of cervical cancer. Persistent infection with high risk-HPV is the required factor for the development of cervical cancer. Objective: The aim of this study was to know the prevalence and distribution of cervical HPV infection in women attending routine cervical cancer screening. Study design: Liquid-based cytology (LBC) of cervical specimens was processed for HPV testing by INNO-LiPA HPV genotyping Extra Reverse Hybridization Line Probe Assay kit. Results: The cytological results of 115 LBCs were: 11(9.6%) negative for intraepithelial lesion or malignancy (NILM), 32(27.8%) atypical squamous cells of undetermined significance (ASC-US), 62(53.9%) low-grade squamous intraepithelial lesion (LSIL) and 10(8.7%) high-grade squamous intraepithelial lesion (HSIL). No cases of cervical cancer were detected. The mean age was 33.78 years ± 10.75 years (range 17-62 years). The overall prevalence DNA HPV detection was 81.7% (94/115), with a large proportion of multiple HPV infection (55.0%). HPV16 was the most common type detected (8.7%) followed by HPV51 (7.8%), HPV52 (5.2%), and HPV66 (2.6%). We found a high proportion of HPV positive cases in all cytological categories, including NLIM cases. Conclusions: These results indicate that prevalence of HPV infection in women attending routine cervical cancer screening is high. Our results confirm the importance of identifying the types of HPV that affect this community to design more effective prevention strategies and thus contribute to the fight against cervical cancer and its precursor lesions.

Prevalence of Human Papillomavirus (HPV) Genotypes and Multiple Infections in Routine Cervical Cancer Screening in a Spanish Regional Population