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The volatile constituents of the seeds of Brassica tournefortii Gouan, growing in Egypt -prepared by simultaneous solvent extraction (steam distillation using Likens–Nickerson type apparatus (SSD-SE) technique) - were investigated by GC/MS analysis. This resulted in the identification of 14 compounds which amount to 76.1% of the total percentage components detected in essential oil of the seeds. Results revealed that the oil was rich in sulphur compounds represented by di-2-propenyltetrasulfide (19.803%) and 3-(methylthio) propyl isothiocyanate (24.39%). Consequently, the cytotoxic activity against two human cancer cell lines; breast (MCF7) and colon (HCT116) were tested and significant results (IC 50 = 1.34 and 4.5 µgmL_1 respectively) were obtained. On the other hand, the in vitro anti oxidant activity was also tested exhibiting significant free radical scavenging effects (IC 50 = 45.17 µg/mL) compared to vitamin c (75.28 µg/mL) which was used as a reference.

Cytotoxic and Antioxidant Activities of the Volatile Constituents of Brassica tournefortii Gouan: Growing in Egypt