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Cefixime trihydrate (CEF) is an oral third generation cephalosporin class of antibiotic. Chemically, it is (6R, 7R)-7{[2-(2-amino-1,3thiazol-4-yl)-2(carboxymethoxyimino)acetyl] amino}-3-ethenyl-8-oxo-5-thia-1 azabicyclo-[4.2.0]oct-2-ene-2 carboxylic acid, clinically used in the treatment of susceptible infections including gonorrhea, otitis media, pharyngitis, lower respiratory-tract infections such as bronchitis, and urinary-tract infections [1,2](Figure 1). It is official in Indian Pharmacopoeia Abstract

international journal of analytical techniques

A Validated Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Estimation of Cefixime Trihydrate and Levofloxacin Hemihydrate in Pharmaceutical Dosage Form