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the variables can eliminate these limitations of “one factor at time” approach. Statistical method has several advantages as being rapid, reliable, less expensive, screening of number of variables, understanding of effect of variable at various coded level [3]. Numbers of statistical models are available amongst them PlackettBurman (PB) and Response Surface Methodology (RSM) is most widely used statistical models. Two level fractional factorial designs (PB design) is used for the screening of the variable with small number of experimental runs instead of using more extensive factorial design, which would furnish more detail explanation [4].

Plackett- Burman Design for the Screening of Media Component for Anthracene Degradation by Sphingobium Yanoikuyae Strain ANT3D