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as home-dialysis. All solutes of dialysis fluid had solved in one can. Because of the solubility, Shaldon had replaced bicarbonate by the buffer precursor acetate. He was able to do this, as he had been a qualified hepatologist. This acetate set-up has not calcification problem at all. This prescription had used for nearly 20 years in the majority of the dialysis centres. Acetate has transformed by the liver into bicarbonate and CO2. In the first hour of the dialysis treatment, there was a loss of the patient’s bicarbonate (> and by this the patient became more acidotic as at start of dialysis), as the liver needed time to transform acetate into bicarbonate and CO2. The centre of Tassin (South France, Charras and Laurent) had treated their patients very successful with acetate dialysis for many decades: A big number of 80 years patients for 30 years dialysis and a second group of patients (90 years) for 40 years dialysis. Tassin had used long treatment times (24 hours per week), Na+ 135 of dialysis fluid and salt intake of 2,0 g per day by own fresh cooking.

Concerning Acidification and Calcification of Dialysis Fluid