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Cytogenetic and molecular studies have shown that human chromosome arm 7q contains a gene that may greatly affect carcinogenesis and progression of human prostate cancer [2,3]. Nitric Oxide (NO) is generated from L-arginine by 3 Nitric Oxide Synthase (NOS) iso-enzymes: neuronal Nitric Oxide Synthase (nNOS), inducible Nitric Oxide Synthase (iNOS), and endothelial Nitric Oxide Synthase (eNOS) [4,5]. The human eNOS gene is located on chromosome 7q35–36 and contains 26 exons.

Effects of the Endothelial Nitric Oxide Synthase (Enos) T786c Genotype on the Risk of Prostate Cancer in Japanese Population