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Immuno-genomics studies realized in Echinodermata (Invertebrates) were surprising. 3 classes out of 5 Echinodermata presented an IGKappa gene and an Fc receptor gene. It was, first demonstrated, in Asterids and Ophuirids. It was, secondly clearly shown, in the ancestral Crinoïd: Antedon bifida.

Evidence of Immune Genes in the Crinoid: Antedon Bifida Evidence of A. Bifida Igkappa Gene, Fc Receptor Gene