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RIPK3 is a member of the receptor-interacting protein kinase family. The RIPK3 protein is a TNFR1-regulated transcription factor that plays an important role in cell stress caused by various factors such as pathogen infection, inflammation, cell differentiation and cell damage. When cells are exposed to external stimuli, RIPK3 activates the downstream transcription factors to cause a series of reactions that ultimately lead to cell survival or death. However, the roles of RIPK3 in lichen planus has not been reported. In this study we compared the expression of RIPK3 protein in normal skin tissue and cutaneous lichen planus lesion, and analyzed the epidemiology characteristics of the patients. It is speculated that RIPK3 may play a role in the development of cutaneous lichen planus.

The Expression And Significance Of RIPK3 In Cutaneous Lichen Planus And The Epidemiological Analysis