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Hepatocellular carcinoma (HCC) is the most common primary liver malignancy worldwide accounting for around 600,000 deaths every year and its incidence has been rising in many countries [1]. In men, it is the fifth most frequently diagnosed cancer worldwide, and the second leading cause of cancerrelated death. In women, it is the seventh most common cancer and the sixth cause of cancer-related death. Despite of significant advances in diagnosis and management, HCC continues to carry a very high case fatality rate [2, 3].

Laboratory Predictors of Risk for Developing Hepatocellular Carcinoma in Cirrhosis