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Inappropriate Sinus Tachycardia (IST), first described in 1979, is a fast heart rhythm arising from the sinus node, the normal primary pacemaker of the heart but at an inappropriately high rate. Many treatments have been suggested for patients with IST; β-adrenergic blockers, even at high doses, generally are ineffective and tend to be associated with other symptoms.

Inappropriate Sinus Tachycardia Mistaken for Relapse of Reentrant Supraventricular Tachycardia in a Young Woman Treated Successfully with Ivabradine