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Background : In early oral squamous cell carcinoma (SCC), neck dissection may be avoided by diagnosis of lymph node metastasis using sentinel lymph node (SLN) biopsy (SNB). Methods : The subjects were 38 patients with stage I or II oral SCC and postoperative follow-up for > 2 years. SLNs were identified by scintigraphy on the day before surgery. During surgery, SLNs were excised and metastasis was evaluated in intraoperative frozen sections. Results : The SLN detection rate was 100%. Four SNB-positive cases underwent radical neck dissection and 34 SNBnegative cases underwent primary tumor resection. Six cases had local recurrence. Of 29 SNB-negative cases without local recurrence, 3 had secondary cervical lymph node metastasis. Three-year overall survival rates were 75% and 89.3% in SNBpositive and SNB-negative cases, respectively. Conclusion : The SNB contributed to avoid unnecessary neck dissection in oral SCC.

Prognosis of Early Stage Oral Squamous Cell Carcinoma Based on Sentinel Lymph node Biopsy for Diagnosis of Cervical Lymph Node Metastasis