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Obesity is closely associated with the development of systemic inflammation and cardiovascular disorders. The aim of our work was to evaluate the effects of aerobic training in absence to control diet on serum interleukin-6 (IL-6) and cardiovascular risk factors in obese women. Methods: Physically inactive, non-trained obese women matched for age (38 ± 5 years of old) and BMI (30 ≤ BMI ≤ 36 kg/m2) that voluntarily participated in the study were randomly divided into exercise (moderate aerobic training, 6 weeks, 3 days/weekly, n=13) and control (no training, n = 13) groups. Pre and post training of anthropometrical markers, fasting serum IL-6 and cardiovascular risk factors were measured in 2 groups. Comparisons within groups were performed by paired Student’s t test and between groups by Student’s independent t test. Results: Exercise group obtained significant decreases in body mass, BMI, body fat % and abdominal obesity as anthropometrical markers (p 0.05). However, aerobic training resulted in significant increase in low density lipoprotein-cholesterol (HDL) and decrease in TG/HDL and LDL/HDL (p < 0.05). Conclusion: Despite a pharmacological property on cardiovascular system, short-time aerobic training does not appear to have an influence on circulating serum IL-6 as inflammatory cytokine in obese females.

The Effects of a Short Term Aerobic Training on Biochemical Cardiovascular Risk Factors and IL-6 in Obese Females