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Purpose:  The novel sodium dodecyl sulfate modified carbon nanotube paste electrode (SDS/ CNTPE) was used as a sensitive sensor for the electrochemical investigation of L-tyrosine (TY).  Methods:  The electrochemical analysis of TY was displayed through cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The surface morphology of SDS/CNTPE and bare carbon nanotube past electrode (BCNTPE) was reviewed trough field emission scanning electron microscopy (FESEM).  Results:  The functioning SDS/CNTPE shows a voltammetric response with superior sensitivity towards TY. This study was conducted using a phosphate buffer solution having neutral pH (pH=7.0). The correlation between the oxidation peak current of TY and concentration of TY was achieved linearly in CV method, in the range 2.0×10 -6 to 5 ×10 -5 M with the detection limit 729 nM and limit of quantification 2.43 μM. The investigated voltammetric study at SDS/CNTPE was also adopted in the examination of TY concentration in a pharmaceutical medicine as a real sample with the recovery of 97% to 98% .  Conclusion:  The modified electrode demonstrates optimum sensitivity, constancy, reproducibility, and repeatability during the electrocatalytic activity of TY.

Design of novel Surfactant Modified Carbon Nanotube PasteElectrochemical Sensor for the Sensitive Investigation of Tyrosineas a Pharmaceutical Drug